Parasitology Research. We demonstrate the tissue localization, in adult Trichinella spiralis , of antigens recognized by Fischer rat sera at 32 weeks postinfection. Immunodominant antigens were located in a wide variety of tissues, including type 1 stichocyte granules, stichocyte cytoplasm, the canalicular tree, hemolymph, hypodermis, hypodermal glands, cord cytoplasm, intestinal-gland cell granules, membranous structures in the midgut epithelium, midgut-occupying substance, brush border, hindgut epithelial cytoplasm, hindgut cuticle, vaginal cuticle, epithelial cytoplasm of the female genital tract, microvilli and discrete areas of the ovum, embryo sheath, intersperm space, discrete areas in immature sperm, small granules and cup-shaped membrane structures of sperm, and exocrine granules in the seminal vesicle and ejaculatory duct. A small amount of antigen was located in the inner layers of the genital portion of the body cuticle.
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CDC - Trichinellosis - Biology
The aim of this study was to characterize the two T. The sequencing results showed that the complete cDNA sequences of the two DNase II enzymes were and bp long, and the predicted open reading frames encoded and amino acids, respectively. Vaccination with the two recombinant DNase II enzymes triggered prominent humoral responses that exhibited significant immune protection against T. Specific antibodies to the two molecules evidently inhibited the in vitro parasite invasion of enterocytes and participated in the killing of NBL by an antibody-dependent cell-mediated cytotoxicity ADCC mode. Trichinella infection is caused by the ingestion of raw or improperly cooked meat of pigs and other animals infected with Trichinella larvae. Human Trichinella infection is principally caused by Trichinella spiralis , and pork and pork products are the dominant infectious source Cui and Wang, ; Murrell and Pozio,
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Parasitology Research in China View all 53 Articles. The most commonly used serodiagnostic antigens for trichinellosis are the excretory-secretory ES antigens from T. The recent studies demonstrated that T. The purpose of this study was to screen early diagnostic antigens in T.
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