I n recent years, US society has seen a sea change in the perception of transgender people, with celebrities such as Caitlyn Jenner and Laverne Cox becoming the recognizable faces of a marginalized population. Transgender rights have also become a mainstream political issue, and the idea that people should be referred to by the names and pronouns they find most fitting—whether or not these designations match those on their birth certificates, or align with the categories of male and female—is gaining acceptance. Yet a biological understanding of the contrast between the natal sex and the gender identity of transgender people remains elusive. In recent years, techniques such as functional magnetic resonance imaging fMRI have begun to yield clues to possible biological underpinnings of the condition known as gender dysphoria.
Transgender People's Brains Are Wired Like Those of Gender They Identify With, New Study Shows
Transsexual differences caught on brain scan | New Scientist
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Transgender vs. Transsexual
NEW YORK Reuters - While President Donald Trump has thrust transgender people back into the conflict between conservative and liberal values in the United States, geneticists are quietly working on a major research effort to unlock the secrets of gender identity. Two decades of brain research have provided hints of a biological origin to being transgender, but no irrefutable conclusions. Now scientists in the consortium have embarked on what they call the largest-ever study of its kind, searching for a genetic component to explain why people assigned one gender at birth so persistently identify as the other, often from very early childhood. Researchers have extracted DNA from the blood samples of 10, people, 3, of them transgender and the rest non-transgender, or cisgender. The project is awaiting grant funding to begin the next phase: testing about 3 million markers, or variations, across the genome for all of the samples.
By Jessica Hamzelou. Doctors could use this information to make a case for delaying puberty to improve the success of a sex change later. Medics are keen to find concrete physical evidence to help those children who feel they are trapped in the body of the opposite sex. One key brain region involved is the BSTc, an area of grey matter.